Interferon Regulatory Factor 4 controls T(H1) cell effector function and metabolism

The transcription factor Interferon Regulatory Factor 4 (IRF4) is essential for T(H2) and T(H17) cell formation and controls peripheral CD8(+) T cell differentiation. We used Listeria monocytogenes infection to characterize the function of IRF4 in T(H1) responses. IRF4(−/−) mice generated only margi...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Mahnke, Justus, Schumacher, Valéa, Ahrens, Stefanie, Käding, Nadja, Feldhoff, Lea Marie, Huber, Magdalena, Rupp, Jan, Raczkowski, Friederike, Mittrücker, Hans-Willi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071867/
https://ncbi.nlm.nih.gov/pubmed/27762344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35521
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