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IL‐12 and IL‐4 activate a CD39‐dependent intrinsic peripheral tolerance mechanism in CD8(+) T cells

Immune responses to protein antigens involve CD4(+) and CD8(+) T cells, which follow distinct programs of differentiation. Naïve CD8 T cells rapidly develop cytotoxic T‐cell (CTL) activity after T‐cell receptor stimulation, and we have previously shown that this is accompanied by suppressive activit...

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Detaylı Bibliyografya
Yayımlandı:Eur J Immunol
Asıl Yazarlar: Noble, Alistair, Mehta, Hema, Lovell, Andrew, Papaioannou, Eleftheria, Fairbanks, Lynette
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071739/
https://ncbi.nlm.nih.gov/pubmed/26990545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545939
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