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CD28 Costimulation Is Required for In Vivo Induction of Peripheral Tolerance in CD8 T Cells

Whereas ligation of CD28 is known to provide a critical costimulatory signal for activation of CD4 T cells, the requirement for CD28 as a costimulatory signal during activation of CD8 cells is less well defined. Even less is known about the involvement of CD28 signals during peripheral tolerance ind...

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Detalhes bibliográficos
Main Authors: Vacchio, Melanie S., Hodes, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193800/
https://ncbi.nlm.nih.gov/pubmed/12515810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021429
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