Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells.

The human multidrug resistance-associated protein MRP confers resistance to various cytotoxic drugs by lowering the intracellular drug concentration. Recent evidence indicates that MRP can also transport glutathione S-conjugates across membranes. To study the transport properties of MRP in intact ce...

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Main Authors: Evers, R, Zaman, G J, van Deemter, L, Jansen, H, Calafat, J, Oomen, L C, Oude Elferink, R P, Borst, P, Schinkel, A H
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC507173/
https://ncbi.nlm.nih.gov/pubmed/8636432
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