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Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells.

The human multidrug resistance-associated protein MRP confers resistance to various cytotoxic drugs by lowering the intracellular drug concentration. Recent evidence indicates that MRP can also transport glutathione S-conjugates across membranes. To study the transport properties of MRP in intact ce...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Evers, R, Zaman, G J, van Deemter, L, Jansen, H, Calafat, J, Oomen, L C, Oude Elferink, R P, Borst, P, Schinkel, A H
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507173/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8636432/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118535
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