Modulation of very low density lipoprotein production and clearance contributes to age- and gender- dependent hyperlipoproteinemia in apolipoprotein E3-Leiden transgenic mice.

Apolipoprotein E3-Leiden (APOE*3-Leiden) transgenic mice have been studied to identify factors modulating chylomicron and VLDL remnant lipoprotein metabolism. Transient elevated levels of VLDL/LDL-sized lipoproteins occurred in these mice with maximal levels during the period of rapid growth (optimu...

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Bibliographic Details
Main Authors: van Vlijmen, B J, van 't Hof, H B, Mol, M J, van der Boom, H, van der Zee, A, Frants, R R, Hofker, M H, Havekes, L M
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC507170/
https://ncbi.nlm.nih.gov/pubmed/8636429
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