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High expression of human beta S- and alpha-globins in transgenic mice: erythrocyte abnormalities, organ damage, and the effect of hypoxia.

A line of transgenic mice with two cointegrated transgenes, the human beta S- and alpha 2-globin genes, linked to the beta-globin locus control region was produced and bred with mice carrying a deletion of the mouse beta major-globin gene. In transgenic mice homozygous for the beta major deletion (a...

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Bibliografische gegevens
Hoofdauteurs: Fabry, M E, Costantini, F, Pachnis, A, Suzuka, S M, Bank, N, Aynedjian, H S, Factor, S M, Nagel, R L
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1992
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC50717/
https://ncbi.nlm.nih.gov/pubmed/1465455
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