Wordt geladen...

Thrombin receptor activation elicits rapid protein tyrosine phosphorylation and stimulation of the raf-1/MAP kinase pathway preceding delayed mitogenesis in cultured rat aortic smooth muscle cells: evidence for an obligate autocrine mechanism promoting cell proliferation induced by G-protein-coupled receptor agonist.

Treatment of quiescent rat aortic smooth muscle cells with either alpha-thrombin or a thrombin receptor-derived agonist peptide (SFLLRNP) resulted in pronounced increases in [3H]thymidine incorporation that were concentration dependent and reached a maximum of approximately 15-fold above serum-starv...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Molloy, C J, Pawlowski, J E, Taylor, D S, Turner, C E, Weber, H, Peluso, M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1996
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC507169/
https://ncbi.nlm.nih.gov/pubmed/8636428
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!