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Clustering with dendritic cells precedes and is essential for T-cell proliferation in a mitogenesis model.

Several antigen-specific immune responses are known to occur in discrete aggregates of dendritic cells (DC) and lymphocytes. We have used a polyclonal model, the mitogenesis of T cells that have been modified with sodium periodate, to evaluate the significance of cell-cell clustering. Firstly, we fo...

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Détails bibliographiques
Auteurs principaux: Austyn, J M, Weinstein, D E, Steinman, R M
Format: Artigo
Langue:Inglês
Publié: 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1454806/
https://ncbi.nlm.nih.gov/pubmed/2835312
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