Synthetic alpha-thrombin receptor peptides activate G protein-coupled signaling pathways but are unable to induce mitogenesis.

alpha-Thrombin (thrombin) stimulates phospholipase C and modulates the activity of adenylate cyclase in a number of cell types via G protein-coupled receptors. It is also a potent growth factor, notably for a line of hamster fibroblasts (CCL39 cells). Recently, predicted amino acid sequences for hum...

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Auteurs principaux: Vouret-Craviari, V, Van Obberghen-Schilling, E, Rasmussen, U B, Pavirani, A, Lecocq, J P, Pouysségur, J
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC275505/
https://ncbi.nlm.nih.gov/pubmed/1312881
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