Synthetic alpha-thrombin receptor peptides activate G protein-coupled signaling pathways but are unable to induce mitogenesis.

alpha-Thrombin (thrombin) stimulates phospholipase C and modulates the activity of adenylate cyclase in a number of cell types via G protein-coupled receptors. It is also a potent growth factor, notably for a line of hamster fibroblasts (CCL39 cells). Recently, predicted amino acid sequences for hum...

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Bibliographic Details

Published in:	Mol Biol Cell
Main Authors:	Vouret-Craviari, V, Van Obberghen-Schilling, E, Rasmussen, U B, Pavirani, A, Lecocq, J P, Pouysségur, J
Format:	Artigo
Language:	Inglês
Published:	American Society for Cell Biology 1992
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275505/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1312881/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.3.1.95
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