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The role of AKT isoforms in glioblastoma: AKT3 delays tumor progression
The growth factor receptor/PI3K/AKT pathway is an important drug target in many cancers including Glioblastoma. AKT, a key node in the pathway, has 3 isoforms, AKT1, AKT2 and AKT3. Here we investigate their role in GBM. We find each activated, ser473 phosphorylated isoform is present in some GBMs bu...
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| Publicado no: | J Neurooncol |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5071179/ https://ncbi.nlm.nih.gov/pubmed/27422127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-016-2220-z |
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