A phase I study of recombinant (r) vaccinia-CEA(6D)-TRICOM and rFowlpox-CEA(6D)-TRICOM vaccines with GM-CSF and IFN-α-2b in patients with CEA-expressing carcinomas

Prime-boost vaccination with recombinant (r) vaccinia(V)-CEA(6D)-TRICOM (triad of co-stimulatory molecules B7.1, ICAM-1 and LFA-3) and rFowlpox(F)-CEA(6D)-TRICOM infect antigen-presenting cells and direct expression of co-stimulatory molecules. We hypothesized that co-administration of vaccine with...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Immunol Immunother
Egile Nagusiak: Duggan, Megan C., Jochems, Caroline, Donahue, Renee N., Richards, Jacob, Karpa, Volodymyr, Foust, Elizabeth, Paul, Bonnie, Brooks, Taylor, Tridandapani, Susheela, Olencki, Thomas, Pan, Xueliang, Lesinski, Gregory B., Schlom, Jeffrey, Carson III, William E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Berlin Heidelberg 2016
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071149/
https://ncbi.nlm.nih.gov/pubmed/27581603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1893-7
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