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Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage.

Proteolysis of triple-helical collagen is an important step in the progression toward irreversible tissue damage in osteoarthritis. Earlier work on the expression of enzymes in cartilage suggested that collagenase-1 (MMP-1) contributes to the process. Degenerate reverse transcription polymerase chai...

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Библиографические подробности
Главные авторы: Mitchell, P G, Magna, H A, Reeves, L M, Lopresti-Morrow, L L, Yocum, S A, Rosner, P J, Geoghegan, K F, Hambor, J E
Формат: Artigo
Язык:Inglês
Опубликовано: 1996
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC507114/
https://ncbi.nlm.nih.gov/pubmed/8609233
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