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Knockdown of the pericellular matrix molecule perlecan lowers in situ cell and matrix stiffness in developing cartilage

The pericellular matrix (PCM) is a component of the extracellular matrix that is found immediately surrounding individual chondrocytes in developing and adult cartilage, and is rich in the proteoglycan perlecan. Mutations in perlecan are the basis of several developmental disorders, which are though...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Xu, Xin, Li, Zhiyu, Leng, Yue, Neu, Corey P., Calve, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070971/
https://ncbi.nlm.nih.gov/pubmed/27578148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2016.08.029
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