Single Molecule Force Measurements of Perlecan/HSPG2: A Key Component of the Osteocyte Pericellular Matrix

Perlecan/HSPG2, a large, monomeric heparan sulfate proteoglycan (HSPG), is a key component of the lacunar canalicular system (LCS) of cortical bone, where it is part of the mechanosensing pericellular matrix (PCM) surrounding the osteocytic processes and serves as a tethering element that connects t...

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Udgivet i:Matrix Biol
Main Authors: Wijeratne, Sithara S., Martinez, Jerahme R., Grindel, Brian J., Frey, Eric W., Li, Jingqiang, Wang, Liyun, Farach-Carson, Mary C., Kiang, Ching-Hwa
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808358/
https://ncbi.nlm.nih.gov/pubmed/26546708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2015.11.001
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