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Perlecan/HSPG2: Signaling Role of Domain IV in Chondrocyte Clustering with Implications for Schwartz-Jampel Syndrome

Perlecan/HSPG2, a large heparan sulfate proteoglycan (HSPG), is indispensable for development of musculoskeletal tissues, where it is deposited within the pericellular matrix (PCM) surrounding chondrocytes and disappears nearly completely at the chondro-osseous junction (COJ) of developing long bone...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Martinez, Jerahme R., Grindel, Brian J., Hubka, Kelsea M., Dodge, George R., Farach-Carson, Mary C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411452/
https://ncbi.nlm.nih.gov/pubmed/30203597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.27521
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