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The role of Bruton’s tyrosine kinase in autoimmunity and implications for therapy
Bruton’s tyrosine kinase (BTK) mediates B cell signaling and is also present in innate immune cells but not T cells. BTK propagates B cell receptor (BCR) responses to antigen-engagement as well as to stimulation via CD40, toll-like receptors (TLRs), Fc receptors (FCRs) and chemokine receptors. Impor...
Shranjeno v:
| izdano v: | Expert Rev Clin Immunol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5070917/ https://ncbi.nlm.nih.gov/pubmed/26864273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/1744666X.2016.1152888 |
| Oznake: |
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