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The Actin-Binding Protein Cofilin and Its Interaction With Cortactin Are Required for Podosome Patterning in Osteoclasts and Bone Resorption In Vivo and In Vitro

The adhesion of osteoclasts (OCs) to bone and bone resorption require the assembly of specific F-actin adhesion structures, the podosomes, and their dense packing into a sealing zone. The OC-specific formation of the sealing zone requires the interaction of microtubule (MT) + ends with podosomes. He...

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Detalles Bibliográficos
Publicado en:J Bone Miner Res
Autores principales: Zalli, Detina, Neff, Lynn, Nagano, Kenichi, Shin, Nah Young, Witke, Walter, Gori, Francesca, Baron, Roland
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070801/
https://ncbi.nlm.nih.gov/pubmed/27064822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2851
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