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The Actin-Binding Protein Cofilin and Its Interaction With Cortactin Are Required for Podosome Patterning in Osteoclasts and Bone Resorption In Vivo and In Vitro

The adhesion of osteoclasts (OCs) to bone and bone resorption require the assembly of specific F-actin adhesion structures, the podosomes, and their dense packing into a sealing zone. The OC-specific formation of the sealing zone requires the interaction of microtubule (MT) + ends with podosomes. He...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Zalli, Detina, Neff, Lynn, Nagano, Kenichi, Shin, Nah Young, Witke, Walter, Gori, Francesca, Baron, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070801/
https://ncbi.nlm.nih.gov/pubmed/27064822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2851
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