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Regulation of amyloid precursor protein processing by its KFERQ motif

Understanding of trafficking, processing, and degradation mechanisms of amyloid precursor protein (APP) is important because APP can be processed to produce β-amyloid (Aβ), a key pathogenic molecule in Alzheimer’s disease (AD). Here, we found that APP contains KFERQ motif at its C-terminus, a consen...

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Detalhes bibliográficos
Publicado no:BMB Rep
Main Authors: Park, Ji-Seon, Kim, Dong-Hou, Yoon, Seung-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070722/
https://ncbi.nlm.nih.gov/pubmed/26779997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2016.49.6.212
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