Increased delta aminolevulinic acid and decreased pineal melatonin production. A common event in acute porphyria studies in the rat.

Tryptophan (TRP) is the precursor of melatonin, the primary secretory product of the pineal gland. Hepatic heme deficiency decreases the activity of liver tryptophan pyrrolase, leading to increased plasma TRP and serotonin. As a paradox, patients with attacks of acute intermittent porphyria (AIP), e...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Puy, H, Deybach, J C, Bogdan, A, Callebert, J, Baumgartner, M, Voisin, P, Nordmann, Y, Touitou, Y
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1996
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC507067/
https://ncbi.nlm.nih.gov/pubmed/8550820
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