Chargement en cours...

Modifications of myelin basic protein in DM20 transgenic mice are similar to those in myelin basic protein from multiple sclerosis.

Transgenic mice containing different numbers of transgenes (2-70) of the myelin proteolipid protein DM20 were phenotypically normal up to 3 mo of age, after which the mice containing 70 copies of the transgene spontaneously demyelinated and died at 10-12 mo. Since we demonstrated that demyelination...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Mastronardi, F G, Mak, B, Ackerley, C A, Roots, B I, Moscarello, M A
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507024/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8567954/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118422
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!