Pathological Hyaluronan Matrices in Cystic Fibrosis Airways and Secretions

Hyaluronan (HA) has been used in treatment of cystic fibrosis (CF) via a nebulizer and has demonstrated success in clinical outcomes. HA is an important glycosaminoglycan that is cross-linked by heavy chains (HCs) from inter–α-inhibitor during inflammation. HC cross-linked HA (HC-HA) becomes signifi...

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Bibliographic Details
Published in:Am J Respir Cell Mol Biol
Main Authors: Matuska, Brittany, Comhair, Suzy, Farver, Carol, Chmiel, James, Midura, Ronald J., Bonfield, Tracey, Lauer, Mark E.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2016
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070107/
https://ncbi.nlm.nih.gov/pubmed/27243106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0358OC
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