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TransComb: genome-guided transcriptome assembly via combing junctions in splicing graphs

Transcriptome assemblers aim to reconstruct full-length transcripts from RNA-seq data. We present TransComb, a genome-guided assembler developed based on a junction graph, weighted by a bin-packing strategy and paired-end information. A newly designed extension method based on weighted junction grap...

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Bibliographische Detailangaben
Veröffentlicht in:Genome Biol
Hauptverfasser: Liu, Juntao, Yu, Ting, Jiang, Tao, Li, Guojun
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069867/
https://ncbi.nlm.nih.gov/pubmed/27760567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1074-1
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