Activating Transcription Factor 4 Is Translationally Regulated by Hypoxic Stress

Hypoxic stress results in a rapid and sustained inhibition of protein synthesis that is at least partially mediated by eukaryotic initiation factor 2α (eIF2α) phosphorylation by the endoplasmic reticulum (ER) kinase PERK. Here we show through microarray analysis of polysome-bound RNA in aerobic and...

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Bibliografiska uppgifter
Huvudupphovsmän: Blais, Jaime D., Filipenko, Vasilisa, Bi, Meixia, Harding, Heather P., Ron, David, Koumenis, Costas, Wouters, Bradly G., Bell, John C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2004
Ämnen:
Gene Expression
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC506979/
https://ncbi.nlm.nih.gov/pubmed/15314157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7469-7482.2004
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