Activating Transcription Factor 4 Is Translationally Regulated by Hypoxic Stress

Hypoxic stress results in a rapid and sustained inhibition of protein synthesis that is at least partially mediated by eukaryotic initiation factor 2α (eIF2α) phosphorylation by the endoplasmic reticulum (ER) kinase PERK. Here we show through microarray analysis of polysome-bound RNA in aerobic and...

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Bibliografske podrobnosti
Main Authors: Blais, Jaime D., Filipenko, Vasilisa, Bi, Meixia, Harding, Heather P., Ron, David, Koumenis, Costas, Wouters, Bradly G., Bell, John C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Gene Expression
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC506979/
https://ncbi.nlm.nih.gov/pubmed/15314157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7469-7482.2004
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