Activating Transcription Factor 4 Is Translationally Regulated by Hypoxic Stress

Hypoxic stress results in a rapid and sustained inhibition of protein synthesis that is at least partially mediated by eukaryotic initiation factor 2α (eIF2α) phosphorylation by the endoplasmic reticulum (ER) kinase PERK. Here we show through microarray analysis of polysome-bound RNA in aerobic and...

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Bibliographic Details
Main Authors:	Blais, Jaime D., Filipenko, Vasilisa, Bi, Meixia, Harding, Heather P., Ron, David, Koumenis, Costas, Wouters, Bradly G., Bell, John C.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology 2004
Subjects:	Gene Expression
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC506979/ https://ncbi.nlm.nih.gov/pubmed/15314157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7469-7482.2004
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Activating Transcription Factor 4 Is Translationally Regulated by Hypoxic Stress

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