Role of Atypical Protein Kinase C in Estradiol-Triggered G(1)/S Progression of MCF-7 Cells

Expression of a dominant negative atypical protein kinase C (aPKC), PKCζ, prevents nuclear translocation of extracellular regulated kinase 2 (ERK-2), p27 nuclear reduction, and DNA synthesis induced by estradiol in human mammary cancer-derived MCF-7 cells. aPKC action upstream of these events has be...

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Hlavní autoři: Castoria, Gabriella, Migliaccio, Antimo, Di Domenico, Marina, Lombardi, Maria, de Falco, Antonietta, Varricchio, Lilian, Bilancio, Antonio, Barone, Maria Vittoria, Auricchio, Ferdinando
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Transcriptional Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC506976/
https://ncbi.nlm.nih.gov/pubmed/15314172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7643-7653.2004
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