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PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells
The p85-associated phosphatidylinositol (PI) 3-kinase/Akt pathway mediates the oestradiol-induced S-phase entry and cyclin D1 promoter activity in MCF-7 cells. Experiments with Src, p85α and Akt dominant-negative forms indicate that in oestradiol-treated cells these signalling effectors target the c...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125704/ https://ncbi.nlm.nih.gov/pubmed/11689445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.21.6050 |
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