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PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells

The p85-associated phosphatidylinositol (PI) 3-kinase/Akt pathway mediates the oestradiol-induced S-phase entry and cyclin D1 promoter activity in MCF-7 cells. Experiments with Src, p85α and Akt dominant-negative forms indicate that in oestradiol-treated cells these signalling effectors target the c...

詳細記述

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書誌詳細
主要な著者: Castoria, Gabriella, Migliaccio, Antimo, Bilancio, Antonio, Di Domenico, Marina, de Falco, Antonietta, Lombardi, Maria, Fiorentino, Roberto, Varricchio, Lilian, Barone, Maria Vittoria, Auricchio, Ferdinando
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC125704/
https://ncbi.nlm.nih.gov/pubmed/11689445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.21.6050
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