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Stratification, Hypothesis Testing, and Clinical Trial Simulation in Pediatric Drug Development
BACKGROUND: Pediatric drug development is plagued by small sample sizes, unvalidated clinical endpoints, and limited studies. OBJECTIVES: The objective of this study was to determine whether age stratification within the pediatric population could be used to (1) assess response to a pharmacologic in...
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| Pubblicato in: | Ther Innov Regul Sci |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5069699/ https://ncbi.nlm.nih.gov/pubmed/27774353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2168479016651661 |
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