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Enrichment Strategies in Pediatric Drug Development: An Analysis of Trials Submitted to the US Food and Drug Administration

Clinical trial enrichment involves prospectively incorporating trial design elements that increase the probability of detecting a treatment effect. The use of enrichment strategies in pediatric drug development has not been systematically assessed. We analyzed the use of enrichment strategies in ped...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Green, Dionna J., Liu, Xiaomei I., Hua, Tianyi, Burnham, Janelle M., Schuck, Robert, Pacanowski, Michael, Yao, Lynne, McCune, Susan K., Burckart, Gilbert J., Zineh, Issam
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441612/
https://ncbi.nlm.nih.gov/pubmed/29218740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.971
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