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Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes

Hormone-secreting cells within pancreatic islets of Langerhans play important roles in metabolic homeostasis and disease. However, their transcriptional characterization is still incomplete. Here, we sequenced the transcriptomes of thousands of human islet cells from healthy and type 2 diabetic dono...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Metab
Hauptverfasser: Segerstolpe, Åsa, Palasantza, Athanasia, Eliasson, Pernilla, Andersson, Eva-Marie, Andréasson, Anne-Christine, Sun, Xiaoyan, Picelli, Simone, Sabirsh, Alan, Clausen, Maryam, Bjursell, Magnus K., Smith, David M., Kasper, Maria, Ämmälä, Carina, Sandberg, Rickard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069352/
https://ncbi.nlm.nih.gov/pubmed/27667667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.08.020
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