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Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes

Hormone-secreting cells within pancreatic islets of Langerhans play important roles in metabolic homeostasis and disease. However, their transcriptional characterization is still incomplete. Here, we sequenced the transcriptomes of thousands of human islet cells from healthy and type 2 diabetic dono...

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Bibliographic Details
Published in:Cell Metab
Main Authors: Segerstolpe, Åsa, Palasantza, Athanasia, Eliasson, Pernilla, Andersson, Eva-Marie, Andréasson, Anne-Christine, Sun, Xiaoyan, Picelli, Simone, Sabirsh, Alan, Clausen, Maryam, Bjursell, Magnus K., Smith, David M., Kasper, Maria, Ämmälä, Carina, Sandberg, Rickard
Format: Artigo
Language:Inglês
Published: Cell Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069352/
https://ncbi.nlm.nih.gov/pubmed/27667667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.08.020
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