Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes

Hormone-secreting cells within pancreatic islets of Langerhans play important roles in metabolic homeostasis and disease. However, their transcriptional characterization is still incomplete. Here, we sequenced the transcriptomes of thousands of human islet cells from healthy and type 2 diabetic dono...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Segerstolpe, Åsa, Palasantza, Athanasia, Eliasson, Pernilla, Andersson, Eva-Marie, Andréasson, Anne-Christine, Sun, Xiaoyan, Picelli, Simone, Sabirsh, Alan, Clausen, Maryam, Bjursell, Magnus K., Smith, David M., Kasper, Maria, Ämmälä, Carina, Sandberg, Rickard
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069352/
https://ncbi.nlm.nih.gov/pubmed/27667667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.08.020
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