Attrition of memory CD8 T cells during sepsis requires LFA-1

CD8 T cell loss and dysfunction have been implicated in the increased susceptibility to opportunistic infections during the later immunosuppressive phase of sepsis, but CD8 T cell activation and attrition in early sepsis remain incompletely understood. With the use of a CLP model, we assessed CD8 T...

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Vydáno v:J Leukoc Biol
Hlavní autoři: Serbanescu, Mara A., Ramonell, Kimberly M., Hadley, Annette, Margoles, Lindsay M., Mittal, Rohit, Lyons, John D., Liang, Zhe, Coopersmith, Craig M., Ford, Mandy L., McConnell, Kevin W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Leukocyte Biology 2016
Témata:
Host Defense & Pathophysiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069090/
https://ncbi.nlm.nih.gov/pubmed/27286793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4A1215-563RR
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