The Ebola Virus VP30-NP Interaction Is a Regulator of Viral RNA Synthesis

Filoviruses are capable of causing deadly hemorrhagic fevers. All nonsegmented negative-sense RNA-virus nucleocapsids are composed of a nucleoprotein (NP), a phosphoprotein (VP35) and a polymerase (L). However, the VP30 RNA-synthesis co-factor is unique to the filoviruses. The assembly, structure, a...

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Udgivet i:PLoS Pathog
Main Authors: Kirchdoerfer, Robert N., Moyer, Crystal L., Abelson, Dafna M., Saphire, Erica Ollmann
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068707/
https://ncbi.nlm.nih.gov/pubmed/27755595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005937
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