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RNA Binding of Ebola Virus VP30 Is Essential for Activating Viral Transcription

The template for Ebola virus (EBOV) transcription and replication is the helical viral nucleocapsid composed of the viral negative-sense (−) RNA genome, which is complexed by the nucleoprotein (NP), VP35, polymerase L, VP24, and VP30. While viral replication is exerted by polymerase L and its cofact...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Biedenkopf, Nadine, Schlereth, Julia, Grünweller, Arnold, Becker, Stephan, Hartmann, Roland K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984652/
https://ncbi.nlm.nih.gov/pubmed/27279615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00271-16
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