Role of Ebola Virus VP30 in Transcription Reinitiation

VP30 is a phosphoprotein essential for the initiation of Ebola virus transcription. In this work, we have studied the effect of mutations in VP30 phosphorylation sites on the ebolavirus replication cycle by using a reverse genetics system. We demonstrate that VP30 is involved in reinitiation of gene...

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Autors principals: Martínez, Miguel J., Biedenkopf, Nadine, Volchkova, Valentina, Hartlieb, Bettina, Alazard-Dany, Nathalie, Reynard, Olivier, Becker, Stephan, Volchkov, Viktor
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Genome Replication and Regulation of Viral Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593317/
https://ncbi.nlm.nih.gov/pubmed/18829754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01395-08
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