Adoptive Transfer of Engineered Rhesus Simian Immunodeficiency Virus-Specific CD8(+) T Cells Reduces the Number of Transmitted/Founder Viruses Established in Rhesus Macaques

AIDS virus infections are rarely controlled by cell-mediated immunity, in part due to viral immune evasion and immunodeficiency resulting from CD4(+) T-cell infection. One likely aspect of this failure is that antiviral cellular immune responses are either absent or present at low levels during the...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Ayala, Victor I., Trivett, Matthew T., Barsov, Eugene V., Jain, Sumiti, Piatak, Michael, Trubey, Charles M., Alvord, W. Gregory, Chertova, Elena, Roser, James D., Smedley, Jeremy, Komin, Alexander, Keele, Brandon F., Ohlen, Claes, Ott, David E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068542/
https://ncbi.nlm.nih.gov/pubmed/27558423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01522-16
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