Adoptive Transfer of Engineered Rhesus Simian Immunodeficiency Virus-Specific CD8(+) T Cells Reduces the Number of Transmitted/Founder Viruses Established in Rhesus Macaques

AIDS virus infections are rarely controlled by cell-mediated immunity, in part due to viral immune evasion and immunodeficiency resulting from CD4(+) T-cell infection. One likely aspect of this failure is that antiviral cellular immune responses are either absent or present at low levels during the...

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Vydáno v:J Virol
Hlavní autoři: Ayala, Victor I., Trivett, Matthew T., Barsov, Eugene V., Jain, Sumiti, Piatak, Michael, Trubey, Charles M., Alvord, W. Gregory, Chertova, Elena, Roser, James D., Smedley, Jeremy, Komin, Alexander, Keele, Brandon F., Ohlen, Claes, Ott, David E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068542/
https://ncbi.nlm.nih.gov/pubmed/27558423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01522-16
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