Adoptive Transfer of Engineered Rhesus Simian Immunodeficiency Virus-Specific CD8(+) T Cells Reduces the Number of Transmitted/Founder Viruses Established in Rhesus Macaques

AIDS virus infections are rarely controlled by cell-mediated immunity, in part due to viral immune evasion and immunodeficiency resulting from CD4(+) T-cell infection. One likely aspect of this failure is that antiviral cellular immune responses are either absent or present at low levels during the...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Ayala, Victor I., Trivett, Matthew T., Barsov, Eugene V., Jain, Sumiti, Piatak, Michael, Trubey, Charles M., Alvord, W. Gregory, Chertova, Elena, Roser, James D., Smedley, Jeremy, Komin, Alexander, Keele, Brandon F., Ohlen, Claes, Ott, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068542/
https://ncbi.nlm.nih.gov/pubmed/27558423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01522-16
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