Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo

Silencing gene expression by siRNAs is rapidly becoming a powerful tool for the genetic analysis of mammalian cells. However, the rapid degradation of siRNA and the limited duration of its action call for an efficient delivery technology. Accordingly, we describe here that Atelocollagen complexed wi...

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Main Authors: Minakuchi, Yoshiko, Takeshita, Fumitaka, Kosaka, Nobuyoshi, Sasaki, Hideo, Yamamoto, Yusuke, Kouno, Makiko, Honma, Kimi, Nagahara, Shunji, Hanai, Koji, Sano, Akihiko, Kato, Takashi, Terada, Masaaki, Ochiya, Takahiro
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2004
Teme:
NAR Methods Online
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC506824/
https://ncbi.nlm.nih.gov/pubmed/15272050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh093
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