Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo

Silencing of gene expression by small interfering RNAs (siRNAs) is rapidly becoming a powerful tool for genetic analysis and represents a potential strategy for therapeutic product development. However, there are no reports of systemic delivery for siRNAs toward treatment of bone-metastatic cancer....

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Hlavní autoři: Takeshita, Fumitaka, Minakuchi, Yoshiko, Nagahara, Shunji, Honma, Kimi, Sasaki, Hideo, Hirai, Kotaro, Teratani, Takumi, Namatame, Nachi, Yamamoto, Yusuke, Hanai, Koji, Kato, Takashi, Sano, Akihiko, Ochiya, Takahiro
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1183487/
https://ncbi.nlm.nih.gov/pubmed/16091473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501753102
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