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Progressive alterations in multipotent hematopoietic progenitors underlie lymphoid cell loss in aging
Declining immune function with age is associated with reduced lymphoid output of hematopoietic stem cells (HSCs). Currently, there is poor understanding of changes with age in the heterogeneous multipotent progenitor (MPP) cell compartment, which is long lived and responsible for dynamically regulat...
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| Udgivet i: | J Exp Med |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5068232/ https://ncbi.nlm.nih.gov/pubmed/27811054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160168 |
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