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Aging-Associated Decrease in the Histone Acetyltransferase KAT6B is Linked to Altered Hematopoietic Stem Cell Differentiation
Aged hematopoietic stem cells (HSCs) undergo biased lineage priming and differentiation toward production of myeloid cells. A comprehensive understanding of gene regulatory mechanisms causing HSC aging is needed to devise new strategies to sustainably improve immune function in aged individuals. Her...
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| 發表在: | Exp Hematol |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7179256/ https://ncbi.nlm.nih.gov/pubmed/32014431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2020.01.014 |
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