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Progressive alterations in multipotent hematopoietic progenitors underlie lymphoid cell loss in aging
Declining immune function with age is associated with reduced lymphoid output of hematopoietic stem cells (HSCs). Currently, there is poor understanding of changes with age in the heterogeneous multipotent progenitor (MPP) cell compartment, which is long lived and responsible for dynamically regulat...
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| Publicado no: | J Exp Med |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5068232/ https://ncbi.nlm.nih.gov/pubmed/27811054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160168 |
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