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Cyclin D1 promotes tumor cell invasion and metastasis by cytoplasmic mechanisms

Amplification of cyclin D1 is a frequent alteration in many cancers of different type and origin. We recently described a novel regulatory axis involving cyclin D1 in the regulation of tumor invasion and metastasis. Membrane-associated cyclin D1-CDK4 complexes promote activation of the small GTPase...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Fusté, Noel P., Ferrezuelo, Francisco, Garí, Eloi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068178/
https://ncbi.nlm.nih.gov/pubmed/27857971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1203471
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