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Cyclin D1 promotes tumor cell invasion and metastasis by cytoplasmic mechanisms
Amplification of cyclin D1 is a frequent alteration in many cancers of different type and origin. We recently described a novel regulatory axis involving cyclin D1 in the regulation of tumor invasion and metastasis. Membrane-associated cyclin D1-CDK4 complexes promote activation of the small GTPase...
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Publicado no: | Mol Cell Oncol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5068178/ https://ncbi.nlm.nih.gov/pubmed/27857971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1203471 |
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