Characterization of cytoplasmic cyclin D1 as a marker of invasiveness in cancer

Cyclin D1 (Ccnd1) is a proto-oncogen amplified in many different cancers and nuclear accumulation of Ccnd1 is a characteristic of tumor cells. Ccnd1 activates the transcription of a large set of genes involved in cell cycle progress and proliferation. However, Ccnd1 also targets cytoplasmic proteins...

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Publicado en:Oncotarget
Autores principales: Fusté, Noel P., Castelblanco, Esmeralda, Felip, Isidre, Santacana, Maria, Fernández-Hernández, Rita, Gatius, Sònia, Pedraza, Neus, Pallarés, Judit, Cemeli, Tània, Valls, Joan, Tarres, Marc, Ferrezuelo, Francisco, Dolcet, Xavier, Matias-Guiu, Xavier, Garí, Eloi
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Pathology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053626/
https://ncbi.nlm.nih.gov/pubmed/27105504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8876
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