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Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin
Cyclin D1 (Ccnd1) together with its binding partner Cdk4 act as a transcriptional regulator to control cell proliferation and migration, and abnormal Ccnd1·Cdk4 expression promotes tumour growth and metastasis. While different nuclear Ccnd1·Cdk4 targets participating in cell proliferation and tissue...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4873647/ https://ncbi.nlm.nih.gov/pubmed/27181366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11581 |
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