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Chromatin-bound MDM2, a new player in metabolism
The oncoprotein MDM2 is recognized as a major negative regulator of the p53 tumor suppressor but growing evidence indicates that its oncogenic activities extend beyond p53. We show that MDM2 is recruited to chromatin independently of p53 to regulate a transcriptional program implicated in amino acid...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5068176/ https://ncbi.nlm.nih.gov/pubmed/27857973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1210560 |
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