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Chromatin-bound MDM2, a new player in metabolism

The oncoprotein MDM2 is recognized as a major negative regulator of the p53 tumor suppressor but growing evidence indicates that its oncogenic activities extend beyond p53. We show that MDM2 is recruited to chromatin independently of p53 to regulate a transcriptional program implicated in amino acid...

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Bibliografiska uppgifter
I publikationen:Mol Cell Oncol
Huvudupphovsmän: Riscal, Romain, Le Cam, Laurent, Linares, Laetitia K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068176/
https://ncbi.nlm.nih.gov/pubmed/27857973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1210560
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