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Chromatin-bound MDM2, a new player in metabolism
The oncoprotein MDM2 is recognized as a major negative regulator of the p53 tumor suppressor but growing evidence indicates that its oncogenic activities extend beyond p53. We show that MDM2 is recruited to chromatin independently of p53 to regulate a transcriptional program implicated in amino acid...
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| Publicat a: | Mol Cell Oncol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5068176/ https://ncbi.nlm.nih.gov/pubmed/27857973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1210560 |
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