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Mdm2 as a chromatin modifier
Mdm2 is the key negative regulator of the tumour suppressor p53, making it an attractive target for anti-cancer drug design. We recently identified a new role of Mdm2 in gene repression through its direct interaction with several proteins of the polycomb group (PcG) family. PcG proteins form polycom...
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| 出版年: | J Mol Cell Biol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5439376/ https://ncbi.nlm.nih.gov/pubmed/27927750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjw046 |
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