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The adenovirus priming protein pTP contributes to the kinetics of initiation of DNA replication
Adenovirus (Ad) precursor terminal protein (pTP) in a complex with Ad DNA polymerase (pol) serves as a primer for Ad DNA replication. During initiation, pol covalently couples the first dCTP with Ser-580 of pTP. By using an in vitro reconstituted replication system comprised of purified proteins, we...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC506811/ https://ncbi.nlm.nih.gov/pubmed/15273278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh726 |
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